The most recent 20 comments posted to Making Light by Spiny Norman:

Show all comments by Spiny Norman.

Posted on entry An Expansion on Palliative Care ::: August 22, 2009, 07:03 PM:
I see no reason to be dainty about this. Charles Krauthammer is a motherfucker.
Posted on entry Iran revolution ::: June 16, 2009, 03:24 AM:
And, of course, always eager to be on the wrong side of history, the neocon hardliners have been voicing their support for... wait for it... for Ahmadinejad! Way to go, assholes.
Posted on entry An astounding misuse of the word "lynch" ::: June 06, 2009, 03:32 PM:
Whoops; I see that I've re-posted Jim's link @2. Apologies.
Posted on entry An astounding misuse of the word "lynch" ::: June 06, 2009, 02:37 PM:
When people on the internets make the error of trivializing the word "lynching," it is useful to refer them here.
Posted on entry Darn those deconstructionists and their crazy rock and roll ::: June 01, 2009, 02:08 PM:
So. I wonder how Kass is doin' with the ol' "wisdom of repugnance" today. There is, after all so much to work with.

Like this
...and this.
Posted on entry Flu Redux ::: April 28, 2009, 11:46 PM:
"Use pump-bottle soap rather than bar soap if you're sharing with others. Some microbes can live surprisingly long times on wet bars of soap."

...But influenza virus is not among them. BAR SOAP AND WARM WATER ARE MORE THAN FINE FOR THE PRESENT PURPOSE.
Posted on entry Flu Redux ::: April 27, 2009, 02:44 AM:
Bassguy @18: as someone who has spent a *lot* of his career at the bench working on the molecular bases of microbial pathogenicity, I think that that allegation is preposterous and foolish.
Posted on entry Flu Redux ::: April 27, 2009, 02:41 AM:
Here's some more reason for concern. In two years, endemic seasonal H1N1 in the United States has gone from ~12% oseltamivir (Tamiflu)-resistant to 98.5% resistant this year.

Reference: JAMA.

The other neuraminidase inhibitor besides tamiflu, zanamivir, is in relatively short supply. Endemic seasonal H1N1 in the U.S. is also 98% resistant to the second class of drugs, the adamantine ion channel inhibitors.

As Jim points out, flu viruses are good at recombining, especially with very similar viruses. The bad news: the Mexican strain is also in the H1N1 subgroup. So, while news reports indicate that the Mexican strain is still Tamiflu-susceptible, it is unlikely to remain so...
Posted on entry Flu Redux ::: April 27, 2009, 02:30 AM:
Pedant point: while a handful of the intercellular messengers that signal infection and control immune responses are enzymes, most of them are not enzymes, because they do not *catalyze* chemical reactions.

Non-enzyme messengers include peptides, among these all of the cytokines (interferon, TNF-alpha, and IL-1 and all of the other interleukins). Other non-enzyme messengers are not peptides, including the prostaglandins and the glucocorticoids.
Posted on entry The secret fighting style of ACORN ::: April 11, 2009, 11:14 PM:
I want to know the crippling self-defense against the MLA handbook. That thing is godawful.
Posted on entry Read this ::: March 29, 2009, 05:49 PM:
Read them both last night, back to back, and then tried to sleep as Cockburn's "They call it Democracy" earwormed into my skull...
Posted on entry The 600 Series Had Rubber Skin ::: March 26, 2009, 11:44 PM:
Re. #65....

Zombie Apocalypse v. Robot Uprising. (Discuss.)
Posted on entry The 600 Series Had Rubber Skin ::: March 26, 2009, 01:44 AM:
I wonder if the Ethical Governor is hooked up to a camera with a spectral detector that can measure melanin? It *is* a project from Georgia Tech, after all...
Posted on entry The 600 Series Had Rubber Skin ::: March 25, 2009, 09:04 PM:
It's soooooooo cute! I think that I will name it "ED-209."
Posted on entry How to Save America ::: March 10, 2009, 05:00 PM:
• Invent something useful.
• Discover something important.
Posted on entry I am your words, failing me, right now ::: March 09, 2009, 01:51 AM:
Evan @ 20: "The one thing I wonder about is -- is the piece trying to extract too much meaning out of the online comments?"

No, it isn't. Remember that about half of the cases are prosecuted for negligent homicide, manslaughter, etc. The reason is that prosecutors, most of them elected, tend to understand the way that a lot of the the folks who vote them into office think; compassion is not a word often heard in such races. Online comments, like votes, can be a form of secret balloting.

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Total: 16 comments. View all these comments on a single page.